Value of QT hysteresis during treadmill exercise test for diagnosing coronary heart disease
10.3760/cma.j.issn.0253-3758.2012.07.010
- VernacularTitle:平板运动负荷试验中QT滞后现象对冠心病的诊断价值
- Author:
Ming-Wei BAO
1
;
Yi-Jie ZHANG
;
Tuan-Tuan TAN
;
Ji-Ning ZHOU
;
Jian-Xue YANG
;
Fang WANG
;
Fei HA
Author Information
1. 武汉大学人民医院
- Keywords:
Coronary disease;
Exercise test;
QT hysteresis index
- From:
Chinese Journal of Cardiology
2012;40(7):589-592
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the value of QT hysteresis index during treadmill exercise test (TET) in diagnosing coronary heart disease (CHD).Methods One hundred consecutive patients suspected for CHD were referred for TET and selective coronary angiography (CAG). Patients were divided into positive [n=55,age (56.0 ±7.9)years] and negative [n =45,age (53.2±6.7)years] group based on their CAG results.For each TET recording,50 points were selected for the RR,QTp,and QTe interval measurements.QTp and QTe interval was plotted against corresponding RR interval.QT/RR curve was constructed by connect all point,QT hysteresis index was calculated for each patient.Results The QTp [(22.4±10.3) msvs.(6.7±4.6) ms,P＜0.001] andQTe [(27.1 ±11.1) ms vs.(7.6±4.6)ms,P ＜ 0.001 ] hysteresis index of patients in positive group were significantly higher than those in negative group.The sensitivity of QTp and QTe hysteresis index for diagnosing CHD was 89.1％ (49/55) and 94.5 ％ ( 52/55 ),respectively,and the specificity was 82.2 ％ ( 37/45 ) and 80.0％ (36/45),respectively.If the patient fulfilled both the classical TET and QT hysteresis criteria,the sensitivity for diagnosing CHD increased to 94.3％ (33/35,QTp) and 94.6％ (35/37,QTe),and the specificity were both 100％ (26/26,26/26).Moreover,QTp ( r =- 0.399,P ＜ 0.001 ) and QTe ( r =- 0.547,P ＜ 0.001 ) hysteresis index highly correlated to Duke treadmill score.Conclusion QT hysteresis index is useful parameter for CHD diagnosis and which could improve the diagnostic value of TET for CHD in combination with the classical TET criteria for diagnosis of CHD.
