Impact of anemia on long-term outcome in elderly patients with acute coronary syndrome undergoing percutaneous coronary interventions
10.3760/cma.j.issn.0253-3758.2012.11.005
- VernacularTitle:贫血与老年急性冠状动脉综合征患者介入治疗后远期病死率的关系
- Author:
Zhe CHI
1
;
Shu-Hua MI
;
Xiao-Xia ZHANG
;
Yang GUAN
;
Quan-Ming ZHAO
;
Xue-Si WU
Author Information
1. 100029,首都医科大学附属北京安贞医院特需医疗科
- Keywords:
Anemia;
Angioplasty,transluminal,percutaneous coronary;
Prognosis
- From:
Chinese Journal of Cardiology
2012;40(11):920-923
- CountryChina
- Language:Chinese
-
Abstract:
Objective To assess the impact of pre-procedure anemia on the long-term mortality in elderly patients with acute coronary syndrome (ACS) after percutaneous coronary interventions.Methods A total of 1014 ACS patients (≥60 years of age) with hemoglobin data and without previous treatment with thrombolytic agents and without end-stage renal failure before the interventional procedure were included.Patients were classified as anemia using the definition of World Health Organization:hemoglobin ＜ 130 g/L in men,and ＜ 120 g/L in women.A total of 253 patients were anemia.The clinical features of patients with and without anemia and association of pre-procedure anemia with long-term mortality were analyzed.Results Incidence of diabetes and serum creatinine level were significantly higher in anemia patients than in non-anemia patients while systolic blood pressure and low-density lipoprotein cholesterol were significantly lower in anemia patients than in non-anemia patients (P ＜ 0.05 or P ＜ 0.01).The patients were followed up for 528(178-675)days.After adjustment for potential co-variants in Cox regression analysis,pre-procedure anemia was associated with a significantly higher long-term mortality (RR:3.293,95％ CI:1.431-7.578,P ＜ 0.01).Conclusion Pre-procedure anemia is an independent predictor of long-term mortality in elderly patients with acute coronary syndrome after percutaneous coronary interventions.
