Liquid chromatography for determination of disulfiramin workplace atmosphere.
- Author:
Sheng FU
1
;
Zhihui HAN
1
;
Keping YU
1
;
Shouquan GAO
1
Author Information
- Publication Type:Journal Article
- MeSH: Air; analysis; Air Pollutants, Occupational; analysis; Chromatography, Liquid; methods; Disulfiram; analysis; Workplace
- From: Chinese Journal of Industrial Hygiene and Occupational Diseases 2015;33(2):133-134
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo establish a method for determination of disulfiram in the workplace atmosphere by liquid chromatography.
METHODSSampling with glass fiber filter, eluting with methanol, separating with C18 column, and determination with liquid chromatography.
RESULTSThe bearing capacity of glass fiber filter exceeded 3.45 mg per piece. The elution efficiency was 97.8%∼101.0% The relative standard deviation varied from 1.09% to 1.44%. The limit of detection was 0.1 µg/ml. The minimum detectable concentration was 0.011 mg/m³ (with sampled air volume of 45 L).
CONCLUSIONThe method has high selectivity, accuracy, and precision and strong applicability.
