Analysis of risk factors of patients with chronic liver failure complicated invasive fungal infections
10.3760/cma.j.issn.1003-9279.2009.03.018
- VernacularTitle:慢性肝衰竭患者侵袭性真菌感染的危险因素分析
- Author:
Yao-Ren HU
1
;
Ai-Rong HU
Author Information
1. 浙江省宁波市传染病医院
- Keywords:
Liver failure;
Fungi;
Risk factors
- From:
Chinese Journal of Experimental and Clinical Virology
2009;23(3):214-217
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the risk factors of chronic liver failure(CLF) complicated invnsive fungal infections(IFI) and prevention and treatment. Methods The clinical data and risk factors of 52 patients with CLF complicated IFI were analyzed retrospectively and were compared with those not complicated IFI. Risk factors were analyzed by chi-square test and Logistic regression test and Ridit test. Results In 52 patients with CLF complicated IFI, there were 69 fungal infections in different tissue and organs, the most were in oral cavity, but other tissue and organs especially bellows infections were rising. Candida albieans infeefions were the most, but cryptococcus neoformans infections and aspergillus infections were rising. The risk factors included species of bacteria infections, serum total bilimbin, hospital days, times of antibiotics using, number of invasive operation,species of antibiotics and degrees of aseites. The mortality of patients with CLF complicated IFI were much higher than those not complicated IFI. Conclusion Patients with CLF complicated IFI have poor progress and prognosis. The effective prevent methods are treating primary disease actively, reducing hospital days, detecting patients' body fluids closely, identifying source of infection as early as possible, using antibiotics correctly, reducing or avoiding invasive operation, using immunoactivators and disinfecting air regularly.
