Study on the epidemiological of rotavirus diarrhea in Lulong in 2008-2009.
- Author:
Dan-Di LI
1
;
Qiu-Li YU
;
Shun-Xiang QI
;
Yun XIE
;
Qing ZHANG
;
Shu-Xian CUI
;
Zhao-Jun DUAN
Author Information
- Publication Type:Journal Article
- MeSH: Age Distribution; Child, Preschool; China; epidemiology; Diarrhea; epidemiology; Female; Humans; Infant; Male; Rotavirus; classification; genetics; isolation & purification; Rotavirus Infections; epidemiology; virology; Seasons
- From: Chinese Journal of Experimental and Clinical Virology 2010;24(1):2-4
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo analyze the feature of epidemiological of rotavirus diarrhea in Lulong county, Hebei province.
METHODS426 stool specimens were collected from inpatant with acute diarrhea from children less than 5 years old. Rotavirus-positive specimens were identified by ELISA kit. G/P typing assays were confirmed with multiplex seminested RT-PCR.
RESULTSRotavirus was detected in 202 of 426 (47.42%) specimens. Genotyping of rotavirus showed that G3 was predominant (57.9%), followed by Gmix (16.3%), G9 (14.9% ), G1 (7.9%), G4 (1%), G2 (0.5%), P-genotyping showed that P [8], Pmix, P [4], P [9], type were found in 58.4%, 28.7%, 6.9% and 1% respectively. The most common G/P combination identified was G3P [8].
CONCLUSIONGroup A rotaviruses was a major pathogen of diarrhea in Children in Lulong. G3P [8] was the predominant type in 2009, Gmix and Pmix abound, and G9 serotypes has become the second predominant after G3 strain in the region.