A clinical study on delayed encephalopathy after carbon monoxide poisoning.
- Author:
Hai YU
1
;
Xiaowen PAN
;
Juan MENG
;
Jianzhang DING
;
Guanghua XU
;
Guangcai FANG
Author Information
- Publication Type:Journal Article
- MeSH: Brain Diseases; etiology; Carbon Monoxide Poisoning; complications; Humans; Retrospective Studies; Tomography, Emission-Computed, Single-Photon
- From: Chinese Journal of Industrial Hygiene and Occupational Diseases 2002;20(1):26-28
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate clinical and imaging characteristics of delayed encephalopathy after carbon monoxide poisoning(DEACMP).
METHODSA retrospective and comparative analysis of neurological manifestations, course, periods of false-cure, prognosis and neuroimaging findings were conducted in 198 patients with DEACMP.
RESULTSOf these patients, 60.1% obtained an initial recovery within 30 d, 23.7% within 31-60 d and 14.6% over 60 d. Total clinical rate was 32.8%, and effectiveness rate 70.1%. According to imaging findings, 15.2% patients were found to have bilateral lesions of basal ganglion, and 70.0% with lesions of subcortical white matter, 12.6% with lesions of two types above mentioned and 2.1% with no lesions. The intervals between onset of illness and initial recovery were (44.6 +/- 10.1), (38.2 +/- 11.9), (61.3 +/- 17.0) d, and (7.5 +/- 2.4) d respectively. Imaging findings can demonstrate the severity of brain injury, but not necessarily parallel to the improvement of illness, for which SPECT proves more useful.
CONCLUSIONSDEACMP is involved in ischemic brain injury and a self-limited illness.
