The product specificity evolution of cyclodextrin glucanotransferase: problems and challenges.
- Author:
Xin-Shuai ZHAO
1
;
Zhan-Kun WANG
;
Qing-Sheng QI
Author Information
1. Life Science School, Shandong University, Jinan 250100, China.
- Publication Type:Journal Article
- MeSH:
Archaeal Proteins;
genetics;
metabolism;
Bacillus;
enzymology;
genetics;
Bacterial Proteins;
genetics;
metabolism;
Biocatalysis;
Cyclodextrins;
metabolism;
Evolution, Molecular;
Glucosyltransferases;
classification;
genetics;
metabolism;
Mutation;
Thermoanaerobacterium;
enzymology;
genetics;
Thermococcus
- From:
Chinese Journal of Biotechnology
2007;23(2):181-188
- CountryChina
- Language:Chinese
-
Abstract:
Cyclodextrin glucanotransferase, the essential enzyme for the production of cyclodextrins, has become the focus of scientific research nowadays. Although many related enzyme properties are well known, the crucial factors in product specificity determination remain to be answered. Here, the recent research progresses of cyclodextrin glucanotransferase, especially those about the evolution of product specificity, were reviewed, and the scientific problems were discussed.
