Pegylated Interferon Alpha2a Induced Panniculitis in Patient with Chronic Hepatitis C.
- Author:
Yoo Sang BAEK
1
;
Jong Yeob KIM
;
Jae Eun CHOI
;
Hyo Hyun AHN
;
Young Chul KYE
;
Soo Hong SEO
Author Information
1. Department of Dermatology, College of Medicine, Korea University, Seoul, Korea. dermaseo@yahoo.co.kr
- Publication Type:Case Report
- Keywords:
Interferon alpha;
Panniculitis
- MeSH:
Alopecia;
Hepatitis C, Chronic;
Hepatitis, Chronic;
Humans;
Interferon-alpha;
Interferons;
Panniculitis;
Pruritus;
Quality of Life;
Ribavirin
- From:Korean Journal of Dermatology
2012;50(7):640-643
- CountryRepublic of Korea
- Language:English
-
Abstract:
Interferon (IFN) alpha is commonly used for the treatment of chronic hepatits C with a combination of ribavirin. There are numerous dermatologic adverse events of IFN, such as xerosis, pruritus, alopecia, and injection site reaction. Panniculitis is one of the rare cutaneous side effects of IFN treatment, which may have a significant reduction on patient's quality of life and may lead to discontinuation of the treatment. Although there have been several reports of panniculitis induced by IFN-beta, IFN-alpha induced panniculitis are rarely reported in the literature. Herein, we report a case of panniculitis caused by pegylated IFN alpha2a injection in a patient with chronic hepatitis C.