Changes in liver function and immune function following laparoscopic and traditional open cholecystectomy: a comparative study.
- Author:
Chun-dong WU
1
;
Dong ZUO
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Antibody Formation; immunology; Cholecystectomy; Cholecystectomy, Laparoscopic; Cholelithiasis; immunology; physiopathology; surgery; Female; Gallbladder Neoplasms; immunology; physiopathology; surgery; Humans; Immunity; Killer Cells, Natural; immunology; Liver; physiopathology; Liver Function Tests; Male; Middle Aged; Polyps; immunology; physiopathology; surgery
- From: Journal of Southern Medical University 2009;29(12):2495-2496
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo compare the effect of laparoscopic cholecystectomy (LC) and open cholecystectomy (OC) on liver function and immune function.
METHODSForty-two patients with normal liver function underwent LC (n=21) or OC (n=21) according to the patients' preference. One day before and 7 days after the operations, the liver functions (ALT, AST, TBIL, ALB) and immune functions (CD3, CD4, CD8, NK cell percentage, IgA, IgM, IgG and C3, C4) of the patients were measured.
RESULTSNo statistical differences were found in the liver functions or immune functions between the two groups after the operation.
CONCLUSIONLC and OC show no significant difference in the effects on the liver function and immune function.
