Studies on chemical constituents of Ranunculus japonicus.
- Author:
Yong-Feng LIANG
1
;
Zuo-Tao CHEN
;
Li-Hong LIU
Author Information
- Publication Type:Journal Article
- MeSH: 1-Butanol; chemistry; Acetates; chemistry; Alkanes; chemistry; Coumarins; chemistry; Drugs, Chinese Herbal; chemistry; Ethanol; chemistry; Flavones; Flavonoids; chemistry; Furans; chemistry; Hydroxybenzoates; chemistry; Luteolin; chemistry; Ranunculus; chemistry; Scopoletin; chemistry; Spectrometry, Mass, Electrospray Ionization
- From: China Journal of Chinese Materia Medica 2008;33(19):2201-2203
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo isolate and determine the chemical constituents of Ranunculus japonicus in Liupan Mountain, Ningxia province, China.
METHODThe herb was extracted with ethanol by ultrasonic bath. The extractives were divided to petroleum ether, ethyl acetate, n-butanol parts. The first two parts were separated and purified with silica gel and Sephadex LH -20 column chromatography. The structures of the separated compounds were idnetefied by physical and chemical properties and spectral analysis.
RESULTNine compounds were isolated and identified as follows: scoparone (1), tricin (2), protocatechuic acid (3), luteolin (4), anemonin (5), scopoletin (6), 5-hydroxy-6, 7-dimethoxyflavone (7), ternatolide (8), 5-hydroxy-7, 8-dimethoxy-flavone (9).
CONCLUSIONCompounds 1-9 were isolated from Ranunculus japonicus for the first time.
