Study on stability of curcumine, demethoxycurcumin and bisdemethoxycurcumin.
- Author:
Gang HAN
1
;
Jing-jing CUI
;
Rui BI
;
Lin-lin ZHAO
;
Wei-guo ZHANG
Author Information
- Publication Type:Journal Article
- MeSH: Chromatography, High Pressure Liquid; Curcumin; analogs & derivatives; chemistry; Drug Stability; Hydrogen-Ion Concentration
- From: China Journal of Chinese Materia Medica 2008;33(22):2611-2614
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the stability of curcumin, demethoxycurcumin and bisdemethoxycurcumin in different buffer solution.
METHODTo determine concentration of curcumin by HPLC when added curcumin, demethoxycurcumin and bisdemethoxycurcumin into the buffer solution the equation of degradation was established.
RESULTThe sequence of stability are bisdemethoxycurcumin > or = demethoxycurcumin > or =curcumin at the same condition.
CONCLUSIONThe demethoxycurcumin can stabilize curcumin more strong than the others. The demethoxycurcumin is a nature stabilizing agent for curcumin.
