Progress of pharmacological research on icariin.
- Author:
Li LI
1
;
Xue-mei WANG
Author Information
1. Department of Integrated Chinese and Western Medicine, First Hospital, Peking University, Beijing 100034, China.
- Publication Type:Journal Article
- MeSH:
Animals;
Cardiovascular System;
drug effects;
Drugs, Chinese Herbal;
pharmacokinetics;
Flavonoids;
pharmacokinetics;
Humans;
Immune System;
drug effects;
Nervous System;
drug effects
- From:
China Journal of Chinese Materia Medica
2008;33(23):2727-2732
- CountryChina
- Language:Chinese
-
Abstract:
Icariin (ICA), as one of the flavones compounds, possess strong pharmacological effects. With wide body distribution, it even could pass through blood-brain barrier into brain tissues. When intaken as a pure compound, distribution of ICA in body was accord with open type of two compartment model. If it is one ingredient of a complex prescription, other component of these could promote the absorption and distribution of ICA. After metabolism, the main component left was its aglycone. A lot of research about ICA based on immunology, phymatology, genesiology and endocrinology sustained it was a valuable compounds. Recently more research about ICA concentrated their interesting to its mysterious effect on bone tissues, cardiovascular system and especially nervous systems.
