Correlativity between fingerprint peaks of HQSM capsule and its relevant herbs.
- Author:
Jian-zhen CHEN
1
;
Gui-yuan LV
;
Su-hong CHEN
;
Lei YE
Author Information
- Publication Type:Journal Article
- MeSH: Capsules; chemistry; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; chemistry; Plants, Medicinal; chemistry
- From: China Journal of Chinese Materia Medica 2008;33(23):2768-2771
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo establish HPLC fingerprint of HQSM capsules,and a new method for correlativity analysis between fingerprint peaks of HQSM and its relevant herbs based on the fingerprint analysis.
METHODThe chromatographic fingerprints of HQSM and its relevant herbs were analyzed by HPLC configured with DAD. The similarity of the HPLC fingerprints between HQSM and its relevant herbs and the comparison of UV spectra of the main peaks in both of fingerprints were used as indices to evaluate the correlativity.
RESULTThe HPLC fingerprint with 16 common peaks was established and the chromatographic peaks were determined.
CONCLUSIONThe established method effectively controlled the quality of HQSM and establised the correlativity between HQSM and its relevant herbs, which would contribute to deduce the chemical components or sources of traditional Chinese medicine prescription.
