Chemical constituents from dried sorophore of cultured Cordyceps militaris.
- Author:
Zi-Ming LV
1
;
Yong-Tao JIANG
;
Li-Jun WU
;
Ke LIU
Author Information
- Publication Type:Journal Article
- MeSH: Cordyceps; chemistry; Culture Techniques; Fruiting Bodies, Fungal; chemistry
- From: China Journal of Chinese Materia Medica 2008;33(24):2914-2917
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the chemical constituents of the dried sorophore of cultured Cordyceps militaris.
METHODCompounds were isolated and purified by macroporous adsorption resin and silica gel column chromatography. Their chemical structures were elucidated on the basis of physicochemical properties and spectral data (IR, FAB-MS, 1H-NMR and 13C-NMR).
RESULTNine compounds were isolated and identified as: ergosta-4, 6, 8 (14)-tetraen-3-one (1), citrostadienol (2), tetracosanoic acid 2, 3-dihydroxypropyl ester (3), ergosterol (4), ergosterol peroxide (5), ergosta-7, 22-dien-3beta, 5alpha, 6beta-triol (6), cordycepin (7), adenosine (8), N-(2-hydroxyethyl) adenosine (9), respectively.
CONCLUSIONCompounds 1-3, 6, 9 were separated from the sorophore of cultured C. militaris for the first time.