Studies on chemical constituents in roots and rhizomes of Notopterygium incisum.

Peng Zhang; Xiu-wei Yang

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Studies on chemical constituents in roots and rhizomes of Notopterygium incisum.

Author: Peng ZHANG ¹ ; Xiu-Wei YANG
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1. State Key Laboratory of Natural and Biomimetic Drugs and Department of Natural Medicines, School of Pharmaceutical Sciences, Peking University, Beijing 100083, China.
Publication Type:Journal Article
MeSH: Apiaceae; chemistry; Drugs, Chinese Herbal; chemistry; isolation & purification; Plant Roots; chemistry; Rhizome; chemistry
From: China Journal of Chinese Materia Medica 2008;33(24):2918-2921
CountryChina
Language:Chinese
Abstract:
OBJECTIVETo study the chemical constituents in the roots and rhizomes of Notopterygium incisum.
METHODThe chemical constituents were isolated by various column chromatographic methods and structurally elucidated by NMR and MS evidences.
RESULTTwenty-four compounds were obtained and identified as isocalamenediol (1), pregnenolone (2), beta-sitosterol (3), bergapten (4), bergaptol (5), cnidilin (6), isoimperatorin (7), bergamottin (8), demethylfuropinnarin (9), nodakenetin (10), 7'-O-methylnotoptol (11), notopterol (12), notoptol (13), pabulenol (14), phenethylferulate (15), p-hydroxyphenethyl anisate (16), trans-ferulic acid (17), nodakenin (18), sucrose (19), 2-methoxy-4-(3-methoxy-1-propenyl)-phenol (20), 3, 4, 5 trimethoxy-trans-cinnamic acid (21), p-methoxycinnamic acid (22), 4-acetoxy-3-methoxy-trans-cinnamic acid (23), and p-hydroxy-trans-cinnamic acid (24).
CONCLUSIONCompounds 1, 14, 20-24 were isolated from the roots and rhizomes of N. incisum for the first time. Compounds 1 and 14 are sesquiterpenoid and coumarin, respectively, and 20-24 were phenylpropanoid compounds.