Progress in co-culture and differentiation in adipose-derived stem cells: a review.
- Author:
Xuqiang NIE
1
;
Huaihong CHEN
;
Ning TANG
;
Ka BIAN
Author Information
1. Murad Research Center for Modernized Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
- Publication Type:Journal Article
- MeSH:
Adipose Tissue;
cytology;
Animals;
Cell Differentiation;
drug effects;
Cells, Cultured;
Coculture Techniques;
methods;
Humans;
Stem Cells;
cytology;
Tissue Engineering
- From:
Chinese Journal of Biotechnology
2011;27(8):1121-1131
- CountryChina
- Language:Chinese
-
Abstract:
Stem cells can be differentiated into many kinds of somatic cells under defined culture conditions. In addition, the homing possess can be partially imitated by co-culture of stem cells with mature somatic cells. Regarding the importance of clinical application of adipose-derived stem cells (ADSCs), our review first introduced the sources and signs of ADSCs, and then the current knowledge of ADSCs co-culture technology, including drug and chemical induced culture, two-dimensional (2D) and three-dimensional (3D) co-culture, mechanisms of ADSCs differentiation, and application development in recent years in details. Finally, we also addressed prospects of ADSCs.
