Study on extraction and drying of Ligusticum chuanxiong in Gan-ning Granule.
- Author:
Yuan-Quan DING
1
;
Shao-Hui WAN
;
Qi-Tai XU
;
Ting-Guo KANG
Author Information
- Publication Type:Journal Article
- MeSH: Coumaric Acids; analysis; chemistry; isolation & purification; Desiccation; methods; Drugs, Chinese Herbal; analysis; chemistry; isolation & purification; Ligusticum; chemistry; Plants, Medicinal; chemistry; Technology, Pharmaceutical; methods
- From: China Journal of Chinese Materia Medica 2007;32(21):2244-2246
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo find out the optimum extract process for Ligusticum chuanxiong in Gan-ning Granule, and studyed the methods of concentration and dry for the extract.
METHODWith the yield of ferulic acid as the assessment index, to optimize the 80% alcohol totalling, extracting times and circumfluence time for extract process by the orthogonal design, to optimize the inlet-air temperature, feed speed and density of feed for spry drying by the orthogonal design.
RESULTThe optimum procedure was the ferulic acid were extracted for 1 hour with 3 times of 80% alcohol. While extracting times effected it most porminently. The optimal processing conditions of spry drying were inlet-air temperature 120 degrees C, feed speed 8.5 mL x min(-1) and density of feed 1.15, While feed speed effected it most porminently.
CONCLUSIONThe experimental results provide the basis for the extraction process and drying process of the ferulic acid in ligusticum chuanxiong.
