Experimental studies on compound Duzhong Jiangya prescription by semi-bionic extraction.
- Author:
Xue-Mei ZHAO
1
;
Xiu-Mei SUN
;
Zhao-Wang ZHANG
;
Jian-Guo HUI
Author Information
- Publication Type:Journal Article
- MeSH: Antihypertensive Agents; chemistry; isolation & purification; Drug Combinations; Drugs, Chinese Herbal; chemistry; isolation & purification; Eucommiaceae; chemistry; Flavonoids; analysis; Glucosides; analysis; Hydrogen-Ion Concentration; Iridoid Glucosides; Iridoids; analysis; Leonurus; chemistry; Plants, Medicinal; chemistry; Proline; analogs & derivatives; analysis; Prunella; chemistry; Scutellaria baicalensis; chemistry; Technology, Pharmaceutical; methods; Time Factors; Triterpenes; analysis; Uncaria; chemistry
- From: China Journal of Chinese Materia Medica 2007;32(21):2247-2252
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVEOptimize the technic condition of Duzhong Jiangya prescription with Semi-bionic Extraction.
METHODUsing homogeneous design, under the same materials granularity, decoction temperature, consumption of water, filtration, concentration, and taking aucubin, hydrochloric acid stachydrine, maloicacid, baicalin, ethanol extract, dry extract as the indexes, the results were comprehensive considered to optimize the semi-bionic extraction condtions.
RESULTThe optimized SBE extraction conditions are the following: pH values of the water for the thrice extraction is 5.845 3, 7.496 1, 8.011 7, and the total extraction time is 3.418 0 h.
CONCLUSIONConsidering the fact of manufacture, the SBE extraction conditions are the following: pH values of the water for the thrice extraction is 6.0, 7.5, 8.0, and the thrice extraction time is 1.5, 1.0, 1.0 h.
