Study on chemical constituents from rhizomes of Actaea asiatica.
- Author:
Jing-Chun GAO
1
;
Jin-Chao ZHANG
;
Yao CHEN
;
Meng-Su YANG
;
Pei-Gen XIAO
Author Information
- Publication Type:Journal Article
- MeSH: Actaea; chemistry; Lanosterol; analogs & derivatives; chemistry; isolation & purification; Plants, Medicinal; chemistry; Rhizome; chemistry; Saponins; chemistry; isolation & purification; Sitosterols; chemistry; isolation & purification; Triterpenes; chemistry; isolation & purification
- From: China Journal of Chinese Materia Medica 2007;32(21):2256-2258
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the chemical constituents of the rhizomes of Actaea asiatica in order to obtain a more comprehensive understanding of its effective components.
METHODCompounds were separated by silica gel chromatography, RP-C18 chromatography and semi-preparative high performance liquid chromatography, and their structures were established by spectral analysis and chemical evidence.
RESULTSix compounds were isolated from the ethyl acetate extract. Their structures were identified as 25-O-acetylcimigenol (1), 12beta-hydroxycimigenol (2), 23-epi-26-deoxyactein (3), 27-deoxyacetylacteol (4), 26-deoxycimicifugenin (5) and beta-sitosterol (6).
CONCLUSIONAll these compounds mentioned above were isolated from the plant for the first time.
