Chemical constituents in unsaponifiable matter from seeds of Trichosanthes hupehensis.

Author: Yan-Bin XI ¹ ; Zhi-Mao CHAO ; Jin WANG
Author Information

1. Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.
Publication Type:Journal Article
MeSH: Oleanolic Acid; analogs & derivatives; chemistry; isolation & purification; Plant Oils; chemistry; isolation & purification; Plants, Medicinal; chemistry; Seeds; chemistry; Sitosterols; chemistry; isolation & purification; Trichosanthes; chemistry; Triterpenes; chemistry; isolation & purification
From: China Journal of Chinese Materia Medica 2007;32(21):2262-2265
CountryChina
Language:Chinese
Abstract:
OBJECTIVETo study the chemical constituents of unsaponifiable matter from the seed oil of Trichosanthes hupehensis.
METHODThe fatty oil from the seeds of T. hupehensis was extracted with petroleum ether. The saponification was carried out with potassium hydroxide. The unsaponifiable matter was isolated and purified by silica gel column chromatography. Their structures were elucidated by means of MS, IR, UV, and 1H-NMR.
RESULTKarounidiol, isokarounidiol, 5-dehydrokarounidiol, 7-oxodihydrokarounidiol, stigmast-7-en-3beta-ol, stigmast-7, 22-dien-3beta-ol, 10alpha-Cucurbitadienol, beta-sitosterol, stigmast-7, 22-dien-3beta-O-beta-D-glucoside were elucidated.
CONCLUSIONAll of these compounds were found in this plant for the first time.