Studies on factors influencing on ephedrine contents in Maxing Shigan decoction.
- Author:
Guang-Yi LIANG
1
;
Zhu-Ying HE
;
Kong-Yun WU
;
Feng-Yun JIN
;
Xing LI
;
Hua FENG
Author Information
- Publication Type:Journal Article
- MeSH: Amygdalin; chemistry; isolation & purification; Calcium Sulfate; chemistry; Drug Combinations; Drugs, Chinese Herbal; chemistry; isolation & purification; Ephedra sinica; chemistry; Ephedrine; analysis; Glycyrrhiza uralensis; chemistry; Herb-Drug Interactions; Materia Medica; chemistry; Plants, Medicinal; chemistry; Prunus; chemistry
- From: China Journal of Chinese Materia Medica 2007;32(24):2600-2603
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the factors influencing on the ephedrine contents in different compositions of Maxingshigan decoction.
METHODAdopt mixed uniform design to dismantle recipes, employ the stepping regression analysis to deal with experimental statistics, use the partial correlational analysis to analyze the correlation coefficients and the results were validated.
RESULTThe regressive equation was of significance, that is Y = 4.36719347 + 7.752707437X1 + 1.2557197041X3 (r = 0.85564, P = 0.0189). The main influencing factors on ephedrine content in Maxingshigan decoction were gypsum and amygdalin. The influent factor of amygdalin on ephedrine content had great significance, and gypsum had significance.
CONCLUSIONThe collective effects of amygdalin and gypsum affect the content of ephedrine in Maxing Shigan decoction which the content-effect relationship was in direct correlation.
