Method and meaning research on skin-test of four injections of traditional Chinese medicine.
- Author:
Wei-Liang WENG
1
;
Hong-Sheng LIN
;
Rui GAO
;
Chang-Huai CHEN
Author Information
1. Xiyuan Hospital, Academy of Chinese Medical Science, Beijing 100091, China. ww6486@126.com
- Publication Type:Journal Article
- MeSH:
Astragalus membranaceus;
adverse effects;
Drug Hypersensitivity;
etiology;
Drugs, Chinese Herbal;
adverse effects;
Humans;
Medicine, Chinese Traditional;
Polysaccharides;
adverse effects;
isolation & purification;
Skin Tests
- From:
China Journal of Chinese Materia Medica
2007;32(24):2649-2652
- CountryChina
- Language:Chinese
-
Abstract:
Huangqi powder injection's positive rate of skin-test was 12.3%. Qingkailing powder injection was 3.0%. Qingkailing injection was 7.6%. Shuanghuanglian injection was 6.3%. Penicillin's rate of allergic reactions was 0.7%-10%. Different form of a drug (power or injection) and different drug consistency could influence the positive rate of skin-test. We don't use drug in positive group, and we use drug in negative group. Some trial subjects still happened allergic reactions in negative group of skin-test. In negative group of skin-test, Huangqi power injection's rate of allergic reactions was 2.1%. Qingkailing injection was 0.4%. Shuanghuanglian injection was 0.9%-2.6%. Shuanghuanglian injection's rate of allergic reactions was 8.6% in all subjects (31/360 include the subjects with positive skin-test and allergic reactions). Qingkailing powder injection's rate of allergic reactions was 4.5% (6/132). Qingkailing injection' s rate of allergic reactions was 9.1% (12/132). Huangqi power injection's rate of allergic reactions was 15.4% (62/402). The total rate of allergic reactions was 10.8%. The main appearance of Penicillin's skin-test was welling under skin, and with some blush. But the main appearance of traditional Chinese medicine skin-test was blush, and with a little welling under skin. Skin-test can reduce the allergic reactions of Qingkailing powder injection, Shuanghuangiian injection, Huangqi power injection. It can be the one measure of reducing adverse reactions.
