Separation and purification of alkaloids from radix of Zanthoxylum nitidum by macroporous adsorption resin.
- Author:
Shao LIU
1
;
Wei ZHANG
;
Peng LEI
;
Xin-Zhong LI
;
Yi-Zeng LIANG
Author Information
- Publication Type:Journal Article
- MeSH: Adsorption; Alkaloids; chemistry; isolation & purification; Porosity; Resins, Plant; chemistry; Zanthoxylum; chemistry
- From: China Journal of Chinese Materia Medica 2008;33(4):377-379
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo obtain the optimal conditions for separating the alkaloids from the extract of Radix of Zanthoxylum nitidum by selecting appropriate macroporous adsorption resins.
METHODEight types of macroporous adsorption were evaluated in separating efficiency with measuring the adsorption ratio and eluting ratio of Alkaloids as indexes.
RESULTThe XDA-5 macroporous adsorption resin had the best separating efficiency. After enrichment and purification with it, the product purity and yield of alkaloids were up to 33.25% and 90.15%, respectively.
CONCLUSIONThis method is simple, feasible and fit for industry production.
