Study on irritation of calcium oxalate crystal in Araceae plants.
- Author:
Hao WU
1
;
Ling-Yun ZHONG
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Araceae; chemistry; Calcium Oxalate; chemistry; isolation & purification; pharmacology; Eye; drug effects; Female; Male; Rabbits; Random Allocation
- From: China Journal of Chinese Materia Medica 2008;33(4):380-384
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo validate the irritation effects of calcium oxalate crystal in several herbal drugs which come from Araceae plants.
METHODCompared the irritation of pure calcium oxalate crystals isolated from the raw rhizome of Typhonium flagelliforme, T. giganteum and Arisaema erubescens and studied the quantity and irritating effect relationship of different concentration suspensions of needle-like calcium oxalate crystals by using the model of rabbits' eyes.
RESULTCalcium oxalate crystals isolated from above three rau rhizome typhonium rhizome showed strong irritation effects on rabbits' eyes. Under the condition of same content of calcium oxalate crystals, there were no difference in irritation effect between the suspensions of raw medicinal materials and pure calcium oxalate crystals. The degree of irritation on rabbits' eyes showed undoubted quantity and irritating effect relationship with the concentrations of Calcium oxalate crystel.
CONCLUSIONCalcium oxalate crystal is the irritant component in some herbal drugs which come from Araceae plants.
