Effects of transcatheter closure of patent ductus arteriosus in 139 adult patients
10.3760/cma.j.issn.0253-3758.2009.11.012
- VernacularTitle:中老年动脉导管未闭患者介入治疗139例分析
- Author:
Xian-Yang ZHU
1
;
Huo-Yuan CHEN
;
Duan-Zhen ZHANG
;
Xiu-Min HAN
;
Xiao-Tang SHENG
;
Chun-Sheng CUI
;
Po ZHANG
;
Qi-Guang WANG
Author Information
1. 沈阳军区总医院
- Keywords:
Ductus arteriosus;
patent;
Heart catheterization;
Middle aged;
Aged
- From:
Chinese Journal of Cardiology
2009;37(11):998-1001
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the clinical feature and the effects of transcatheter closure of adult patients with patent ductus arteriosus (PDA). Methods Between January 2000 and April 2009, 139 patients [22 male, aged from 40 to 74:(49.8±6.8) years] with PDA were hospitalized in our hospital. Clinical data and effects of transcatheter closure of PDA were analyzed. Results There were 64 patients with NYHA class Ⅰ, 53 with class Ⅱ, 16 with class Ⅲ and 6 with class Ⅳ before procedure. In 139 patients, pulmonary arterial hypertension (PAH) was found in 107 out of 139 patients (77.0%). Transcatheter PDA closure was not performed in 3 patients due to severe PAH and successfully performed in the remaining 136 patients (97.8%) without major complications. Post procedure aortic angiography evidenced minor residual shunt in 14 cases, small residual shunt in 2 cases and moderate shunt in 1 case. The NYHA class was significantly improved and the PAH significantly reduced [sPAP: (47.3±23.9)mm Hg(1 mmHg=0.133 kPa) vs. (28.1±12.3) mm Hg,P<0.01] post procedure. Conclusion PAH and heart failure were commonly associated with PDA in adult patients. Transcatheter PDA closure is safe and effective in these patients except those with severe PAH.
