Chronic outcome of patients with paroxysmal atrial fibrillation post catheter ablation
10.3760/cma.j.issn.0253-3758.2009.12.011
- VernacularTitle:阵发性心房颤动导管消融的远期随访研究
- Author:
Yu-Bi LIN
1
;
Yun-Long XIA
;
Tian-Jun GAO
;
Zhen-Liang CHU
;
Pei-Xin CONG
;
Dong CHANG
;
Xiao-Meng YIN
;
Shu-Long ZHANG
;
Dong-Hui YANG
;
Yan-Zong YANG
Author Information
1. 大连医科大学附属第一医院
- Keywords:
Atrial fibrillation;
Catheter ablation;
Prognosis
- From:
Chinese Journal of Cardiology
2009;37(12):1101-1104
- CountryChina
- Language:Chinese
-
Abstract:
Objective High short-term successful rate was reported for catheter ablation in patients with paroxysmal atrial fibrillation ( AF) , we analyzed the long-term outcome (success rate, anticoagulation therapy and embolism event, anti-arrhythmic therapy and death post procedure) of catheter ablation for paroxysmal AF in this study. Methods From January 2000 to December 2004, 106 consecutive patients with drug-refractory paroxysmal AF underwent catheter ablation and were followuped for (60. 7 ± 11.8) months. Segmental pulmonary vein isolation (SPVI) was routinely performed by radiofrequency energy under the guidance of circular mapping catheter. The patients were followed up with 24 h-holter, ECG, telephone or letter. Data on recurrence of AF, the anticoagulation medication and the incidence of embolism, anti-arrhythmic therapy were obtained. Results There were 9 patients lost to follow up. In the remaining 97 patients [65 males, (54. 8 ±11.2) years old] , 3 cases died from cancer, sinus rhythm was maintained in 68 patients (Group S, 72. 3% ) and AF recurrence evidenced in 26 patients (Group R, 27.7% ). In Group S, 56 patients (82. 4% ) discontinued anticoagulation medication, and 12 patients continued to take aspirin. There was no embolism event in Group S during follow-up. In Group R, 1 patient continued to take warfarin; 11 patients continued to take aspirin and 2 patients suffered from cerebral embolism. Anticoagulation medication was discontinued in 14 patients (53. 8% ) and 1 patient suffered form cerebral embolism. The incidence of embolism event in Group R is significantly higher than in Group S (P <0. 01). More patients discontinued anti-arrhythmic medication in Group S than in Group R ( 80. 9% vs. 56. 0% , P < 0. 05 ). Conclusion Catheter ablation is associated with satisfactory long-term success rate, reduced anti-arrhythmia medication, improved quality of life in patients with paroxysmal AF.
