A Case of HMB-45 Negative Hypopigmented Cellular Blue Nevus.
- Author:
Mi Woo LEE
1
;
Jee Ho CHOI
;
Kyung Jeh SUNG
;
Kee Chan MOON
;
Jai Kyoung KOH
Author Information
1. Department of Dermatology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
HMB-45;
Hypopigmented cellular blue nevus
- MeSH:
Immunohistochemistry;
Melanocytes;
Melanoma;
Nevus;
Nevus, Blue*;
Nevus, Epithelioid and Spindle Cell;
Nevus, Intradermal;
S100 Proteins
- From:Korean Journal of Dermatology
2002;40(2):191-194
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Blue nevus is a benign pigmented lesion of dermal melanocytes with a number of histologic and clinical variants. We report a variant of cellular blue nevus that is minimally pigmented. Immunohistochemistry showed the case to be strongly positive with S-100 protein, but negative with Ki-67 and HMB-45 antibody. There is a potential for hypopigmented cellular blue nevus to be confused with other benign nevus, such as intradermal nevus, Spitz nevus, and deep penetrating nevus and malignant melanoma.
