Impact of age and gender on cardiac structure and function in normal Chinese population
10.3760/cma.j.issn.0253-3758.2010.01.015
- VernacularTitle:正常人群年龄进程中心脏结构和功能的变化特点
- Author:
Jing LI
1
;
Yan-Ling LIU
;
Qing HE
;
Qi HUA
;
Hong-Qi XUE
;
Jing GAO
;
Jian-Peng WANG
;
Xiu-Zhang L(U)
;
Zhen-Hui ZHU
;
Yan LING
;
Hai-Rong FAN
;
Chuan-Yu WANG
Author Information
1. 卫生部北京医院
- Keywords:
Heart;
Ventricular function,left;
Echocardiography
- From:
Chinese Journal of Cardiology
2010;38(1):52-56
- CountryChina
- Language:Chinese
-
Abstract:
Objective To identify the impact of age and gender on cardiac structure and left ventricular function in normal Chinese by echocardiography. Methods Cardiac structure, valve flow velocity and cardiac function were measured by echocardiography in 15 692 healthy volunteers. Subjects were grouped by age at 5 years interval in population older than 5 years. Children under 5 years were divided into 3 age groups(<1 years,1-3 years,4-5 years). Hierarchical cluster analyses were performed for ages, based on indexes of cardiac structure and function respectively. Results Six groups (< 1 years, 1-3 years,4-5 years, 6-10 years, 11-20 years, ≥21 years) were generated after the age hierarchical cluster analyses based on index of cardiac structure. Four groups (≤30 years, 31-50 years, 51-80 years,≥81 years) were generated based on spectral current flow. Six groups (< 1 years,1-3 years,4-5 years, 6-10 years, 11-15 years, ≥16 years) were generated baaed on left ventricular systolic function and five groups (≤15 years, 16-30 years, 31-50 years, 51-80 years, ≥81 years) were generated based on left ventricular diastolic function. Cardiac structure index were similar between male and female in age groups ≤ 10 years and significantly lower in females than males in age groups ≥ 11 years (P < 0.05). Valve flow velocity was similar between male and female in various age groups (P >0.05). Left ventricular systolic function was similar between male and female in age groups ≤10 years but was significantly higher in males than females in age groups ≥11 years(all P <0.05). Left ventricular diastolic function was similar between female and male in various age groups (P > 0.05) and equally decreased with aging in both female and male subjects. Conclusions The cardiac development in Chinese population can be divided in 6 phases and becomes stable in subjects older than 21 years, left ventricular systolic function becomes stable in subjects older than 16 years and the left ventricular diastolic function declines physiologically with aging.
