Diagnosis and treatment of esthesioneuroblastoma in the nasal cavity and sinuses.

Author: Chao CHENG ¹ ; Xiao bin LONG
Author Information

1. Department of Otorhinolaryngology-Head and Neck Surgery, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, China.
Publication Type:Journal Article
MeSH: Adult; Esthesioneuroblastoma, Olfactory; diagnosis; therapy; Female; Humans; Male; Middle Aged; Nasal Cavity; Nose Neoplasms; diagnosis; therapy; Paranasal Sinus Neoplasms; diagnosis; therapy; Retrospective Studies; Young Adult
From: Journal of Southern Medical University 2010;30(10):2402-2405
CountryChina
Language:Chinese
Abstract:
OBJECTIVETo discuss the clinical characteristics, diagnosis and treatment of esthesioneuroblastoma (ENB).
METHODSThe clinical data of 7 patients with ENB were analyzed retrospectively, and the clinical characteristics, diagnosis, surgical approaches and prognosis of the disease were discussed.
RESULTSThe 7 patients received surgical treatment combined with radiotherapy and chemotherapy. Tumor relapse occurred within one year in two cases, which were treated with a second operation combined with radiotherapy, and one patient died and one survived with tumor after a one-year follow-up.
CONCLUSIONEarly diagnosis of ENB can be difficult. Transnasal-frontal approach with nasal endoscope is effective approach to ENB treatment, and the patients may benefit from postoperative radiotherapy and chemotherapy to improve the prognosis.