Transforming of the drug resistance plasmid from Staphylococcus aureus into Escherichia coli.
- Author:
Wan-kelan LI
1
;
Hong JIANG
;
Yong-fen HUANG
;
Xue-qin WAN
Author Information
- Publication Type:Journal Article
- MeSH: Drug Resistance, Bacterial; genetics; Escherichia coli; drug effects; genetics; Plasmids; Staphylococcus; genetics; Transformation, Bacterial
- From: Journal of Southern Medical University 2010;30(11):2482-2484
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo discuss the possible mechanism of drug resistance transmission between Staphylococcus and Escherichia coli.
METHODSThe chloramphenicol resistance plasmid of Staphylococcus aureus was extracted to transform the sensitive Escherichia coli, and the drug-resistant Escherichia coli were screened by drug sensitivity test.
RESULTSThe drug-resistant Escherichia coli were successfully obtained.
CONCLUSIONStaphylococcus may have a natural shuttle plasmid of drug resistance, which can transform Escherichia coli under specific conditions.
