Advances in researches on inhibin B and male reproduction.
- Author:
Ren-liang LI
1
;
Xiao-mei ZHANG
Author Information
1. Department of Reproduction & Genetics, the First Peoples Hospital of Yunnan Province, Kunming, Yunnan 650031, China. KmLRL2004@yahoo.com.cn
- Publication Type:Journal Article
- MeSH:
Fertility;
physiology;
Humans;
Inhibins;
analysis;
physiology;
Male;
Reproductive Techniques, Assisted;
Spermatogenesis;
physiology
- From:
National Journal of Andrology
2005;11(4):299-302
- CountryChina
- Language:Chinese
-
Abstract:
Inhibin B, a dimeric glycoprotein, is directly secreted by the testis and responses to a diversity of exogenic hormones. Serum inhibin B levels will be influenced by different factors, such as age, testis volume, the time of puberty, the time of sample collection, varied groups of people and so on. Inhibin B is directly relevant to spermatogenesis of the testis and can be viewed as a valuable marker to assess male fertility. The determination of serum inhibin B has an applicable value in diagnosing the etiology of male infertility, assessing the damage to spermatogenesis in men after radiotherapy or chemiotherapy, and evaluating therapeutic effect on cryptorchidism and varicocele. Moreover, as far as assisted reproductive technology is concerned, the investigation of serum inhibin B has a predictive value in testicular sperm extraction.
