Omission factors in detecting early stage prostate cancer by TRUS needle biopsy.
- Author:
Shi-Wei ZHANG
1
;
Hong-Qian GUO
;
Wei-Dong GAN
;
Zhen-Hua GONG
;
Ze-Yu SUN
Author Information
- Publication Type:Journal Article
- MeSH: Aged; Aged, 80 and over; Biopsy, Needle; methods; Diagnostic Errors; Humans; Male; Middle Aged; Neoplasm Staging; Prostate; pathology; Prostatic Neoplasms; diagnosis; diagnostic imaging; pathology; Rectum; diagnostic imaging; Transurethral Resection of Prostate; Ultrasonography, Interventional
- From: National Journal of Andrology 2005;11(6):431-437
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo analyze and reduce the omission factors in detecting early stage prostate cancer by TRUS needle biopsy, and to improve the diagnosis of the disease.
METHODSA total of 80 benign prostatic hyperplasia patients suspected of prostatic carcinoma underwent TRUS sextant biopsies. The pathological results being negative, the patients received transurethral resection of the prostate (TURP).
RESULTSAfter TURP, 25 cases were pathologically diagnosed as prostate cancer, with an omission rate of 31.25% (25/80). Of the diagnosed cancer patients, 10 were treated by radical perineum prostatectomy, 8 by surgical castration, and 7 by medical castration.
CONCLUSIONSome tumors may fail to be detected by TRUS needle biopsy. Serial or multi-core needle biopsies can decrease the omission rate in the diagnosis of organ confined cancer.