The Difference of Left Ventricular Hypertrophy and the Diastolic Function between Prehypertensives and Normotensives.
10.4070/kcj.2006.36.6.437
- Author:
Hyo Suk AHN
1
;
Soo Joong KIM
;
Myeong Kon KIM
;
Chung Whee CHOUE
;
Kwon Sam KIM
;
Jung Sang SONG
;
Jong Hoa BAE
Author Information
1. Department of Cardiology, Kyung Hee University Medical Center, Seoul, Korea. soojoong@dreamwiz.com
- Publication Type:Original Article
- Keywords:
Left ventricular hypertrophy
- MeSH:
Cardiovascular Diseases;
Echocardiography;
Electrocardiography;
Female;
Humans;
Hydrogen-Ion Concentration;
Hypertension;
Hypertrophy, Left Ventricular*;
Male;
Prevalence
- From:Korean Circulation Journal
2006;36(6):437-442
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND AND OBJECTIVES: We investigated whether prehypertensives (PHs) exhibit more prevalent electrocardiographic and echocardiographic left ventricular hypertrophy (ECG LVH) and if they are are more associated with impaired left ventricular (LV) diastolic function than are normotensives (NTs). SUBJECTS AND METHODS: A total of 608 subjects> or = 40 years of age with normal BP (SBP<120 mmHg and DBP<80 mmHg, n=335) and PH (n=273) and who were without a history of hypertension, diabetes and any other known cardiovascular diseases underwent blood sampling for obtaining the lipid profile, and they also underwent 12-lead electrocardiography and echocardiography. RESULTS: Compared with the NTs, the PHs had significantly higher Sokolow-Lyon and Cornell voltage for ECG LVH, and they ahd a higher prevalence of ECG LVH (men: 16.9% vs 5.9%, women: 2.0% vs 1.0%, respectively). The PHs had a more increased left ventricular mass index (LVMI, Men: 118.1+/-24.4 g/m2 vs 102.0+/-19.1 g/m2, p=0.02; Women: 117.5+/-26.4 g/m2 vs 101.9+/-30.7 g/m2, p=0.02) and a more decreased LV diastolic function (E/A, Men: 1.14+/-0.6 vs 1.30+/-0.4, p=0.03; Wemen: 1.11+/-0.6 vs 1.25+/-0.5, p=0.03) on echocardiography than the NTs. CONCLUSION: The PHs were associated with a higher prevalence of ECG LVH and a more increased LVMI on echocardiography than that of the NTs. Therefore, we should pay earlier attention to diagnose and screen the pre-hypertensive group.
