Immunohistochemical study of caveolin-1 and -2 in the rat retina.
10.4142/jvs.2006.7.2.101
- Author:
Heechul KIM
;
Taeki LEE
;
Jeeyoung LEE
;
Meejung AHN
;
Changjong MOON
;
Myung Bok WIE
;
Taekyun SHIN
- Publication Type:Original Article ; Research Support, Non-U.S. Gov't
- Keywords:
caveolin;
immunohistochemistry;
rat;
retina
- MeSH:
Animals;
Caveolin 1/*analysis/immunology;
Caveolin 2/*analysis/immunology;
Gene Expression Regulation;
Immunohistochemistry;
Male;
Rats;
Rats, Sprague-Dawley;
Retina/*chemistry
- From:Journal of Veterinary Science
2006;7(2):101-104
- CountryRepublic of Korea
- Language:English
-
Abstract:
The expression of caveolin-1 and -2 in the retina was examined; Western blot analysis showed that both were present. Immunohistochemistry indicated that caveolin-1 was expressed in the majority of retinal layers, including the ganglion cell layer, inner plexiform layer, outer plexiform layer, and in the vascular endothelial cells of the retina. Caveolin-2 was primarily immunostained in the vessels, but in a few other elements as well. This is the first demonstration of caveolin differential expression in the retina of rats, and suggests that caveolin plays an important role in signal transduction in glial cells and neuronal cells.
