Sesquiterpenes and an intermediate 1alpha, 6beta, 11-eudesmanetriol in the biosynthesis of geosmin from Streptomyces sp.
- Author:
Ya-Bin YANG
1
;
Zhi YANG
;
Xue-Qiong YANG
;
Yong ZHANG
;
Li-Xing ZHAO
;
Li-Hua XU
;
Zhong-Tao DING
Author Information
1. Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education, School of Chemical Science and Technology, Yunnan University, Kunming 650091, China.
- Publication Type:Journal Article
- MeSH:
Magnetic Resonance Spectroscopy;
Molecular Structure;
Naphthols;
chemistry;
isolation & purification;
Sesquiterpenes;
chemistry;
isolation & purification;
Streptomyces;
chemistry
- From:
Acta Pharmaceutica Sinica
2012;47(3):364-366
- CountryChina
- Language:English
-
Abstract:
One new sesquiterpene was isolated from the fermentation broth of Streptomyces sp. and the structure was elucidated by spectral analysis as caryolane-1, 6beta-diol (1). An intermediate 1alpha, 6beta, 11-eudesmanetriol (2) in the biosynthesis of geosmin was also found in this strain which proved sequence for the reactions, especially bicyclization preceding dealkylation.
