Application of BED-CEIA to estimate the human immunodeficiency virus prevalence among injecting drug users in Chongqing municipality.
- Author:
Mei HAN
1
;
Yu-lin WANG
;
Min-jie WANG
;
Quan-hua ZHOU
;
Yan JIANG
Author Information
- Publication Type:Journal Article
- MeSH: AIDS Serodiagnosis; methods; China; epidemiology; Drug Users; HIV Antibodies; blood; HIV Infections; blood; epidemiology; HIV Seroprevalence; Humans; Immunoenzyme Techniques; Incidence; Population Surveillance; Prevalence; Substance Abuse, Intravenous; epidemiology; virology; Urban Population; statistics & numerical data
- From: Chinese Journal of Epidemiology 2007;28(11):1077-1080
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo estimate the human immunodeficiency virus (HIV-1) prevalence of injecting drug users (IDUs) in Chongqing city.
METHODSTo apply BED-capture enzyme immunoassay (CEIA) which was based on the principle of HIV-antibody varies as the disease progress, in order to estimate both the HIV incidence and prevalence of IDUs from two IDUs surveillance sites in Chongqing.
RESULTSDuring the research period, 4711 serum samples were tested by ELISA and 130 were HIV-1 positive, confirmed by Western blot. The prevalence of IDUs surveillance site A from 1999 to 2006 were 0.73%, 2.02%, 1.54%, 2.96% and 2.80%, and the incidence rates were 0.57%, 0.93%, 0,1.24% and 1.68% respectively. The prevalence of IDUs surveillance site B appeared to be 4.21%, 9.96%, 8.13%, and the incidence rates were 0.95%, 1.04% and 0.90% respectively, from 2004 to 2006.
CONCLUSIONMany of the IDUs HIV carriers in Chongqing had been infected for long time, and the incidence rates among them were steady, keeping at the same level for 1-2 years. Promotion on intervention for IDUs had produced certain effects but more attention still needs to be paid.
