Effect of micronutrients on the immune status of human immunodeficiency virus-positive individuals.
- Author:
Fei ZHAO
1
;
Xue-Ling FENG
;
Wei XU
;
Yan-Min MA
;
Zhe WANG
;
Wen-Jie LI
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Dietary Supplements; HIV Infections; drug therapy; immunology; Humans; Micronutrients; therapeutic use; Middle Aged
- From: Acta Academiae Medicinae Sinicae 2010;32(3):340-342
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo evaluate the effect of micronutrients on the immune status of human immunodeficiency virus (HIV)-positive individuals.
METHODSTotally 102 HIV-positive individuals were randomly divided into supplementation group (received micronutrients supplement) and control group (received placebo). Physical examinations were performed at baseline and at the end of the trial. Immune status were determined in both two groups.
RESULTSAge, height, weight, and sex ratio were not significantly different between two groups (all P>0.05). Baseline CD3+, CD4+, and CD8+ T lymphocytes and IgA, IgG, IgM, C3 levels were not significantly different between two groups (all P>0.05), while the levels of CD3+, CD4+, and CD8+ T lymphocytes and IgA, IgG, IgM, C3 were significantly higher in supplementation group than in control group(all P0.05).
CONCLUSIONSupplementation of micronutrients can improve the immune status of HIV-positives individuals.
