Prognostic factors and fertility outcomes of borderline ovarian tumors after conservative surgery.
- Author:
Tao TAO
1
;
Dong-yan CAO
;
Jia-xin YANG
;
Keng SHEN
;
Jing-he LANG
;
Li-na GUO
Author Information
- Publication Type:Journal Article
- MeSH: Adolescent; Adult; Female; Fertility; Follow-Up Studies; Humans; Middle Aged; Neoplasms, Glandular and Epithelial; surgery; Ovarian Neoplasms; surgery; Prognosis; Retrospective Studies; Treatment Outcome; Young Adult
- From: Acta Academiae Medicinae Sinicae 2010;32(5):488-492
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo evaluate the prognostic factors and fertility outcomes of borderline ovarian tumors (BOT) after conservative surgery.
METHODSThe clinical data of 109 patients with BOT who were treated in Peking Union Medical College Hospital from January 1990 to December 2007 were retrospectively analyzed. According to the FIGO staging system,there were 34(31.2%) patients at Stage Ia and Ib, 66 (60.6%) at Stage Ic, 2 (1.8%) at Stage II and 7(6.4%) at stage III. No patient was at Stage 4.
RESULTSSurgical treatment included comprehensive staging surgery (n=40, 36.7%), ovarian cystectomy (n=27,24.8%), and unilateral salpingo-ovariectomy (n=42, 38.5%). The average follow-up period was (60.3±42.5) months. Relapse occurred in 25 patients (22.9%), and the mean duration from therapy to recurrence was (36.1±31.9) months. Only one patient died of BOT. Multivariate analysis showed that surgery procedure and tumor stage were the independent prognostic factors affecting recurrence. Of 66 patients with the desire of fertility, 24 (36.4%) finally got pregnant.
CONCLUSIONSConservative surgery has comparatively good prognosis and should be the first choice for younger patients with the desire of fertility. The high-risk factors should be evaluated before the initiation of treatment.
