Comparison of PSAD and PSAD-TZ value in prostatic hyperplasia and prostatic cancer.
- Author:
Qiang FU
1
;
De-Hong YAO
;
Yue-Qing JIANG
Author Information
- Publication Type:Journal Article
- MeSH: Aged; Aged, 80 and over; Diagnosis, Differential; Humans; Male; Middle Aged; Predictive Value of Tests; Prostate; pathology; Prostate-Specific Antigen; blood; Prostatic Hyperplasia; diagnosis; Prostatic Neoplasms; diagnosis
- From: National Journal of Andrology 2002;8(6):411-413
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVESTo compare PSAD, PSAD-TZ, PSA, FPSA/TPSA detection used in diagnosis of prostatic hyperplasia(BPH) and prostatic cancer(PCa).
METHODSFourty-three cases of BPH and twenty cases of PCa with PSA < 20 micrograms/L were chosen, then compared PSA, PSAD, FPSA/TPSA, PSAD-TZ between BPH and PCa.
RESULTSThe mean PSA in BPH and PCa is (10.47 +/- 6.25) microgram/L and (13.92 +/- 3.20) microgram/L respectively with no statistic difference (P > 0.05). The mean PSAD in BPH and PCa is (0.15 +/- 0.12) microgram/L and (0.24 +/- 0.13) microgram/L respectively with statistic difference (P < 0.05). The mean FPSA/TPSA in BPH and PCa is (0.58 +/- 0.42) microgram/L and (0.26 +/- 0.17) microgram/L respectively with statistic difference (P < 0.05). The mean PSA-TZ in BPH and PCa is (0.26 +/- 0.22) and (0.51 +/- 0.28) respectively with obviously statistic difference (P < 0.01).
CONCLUSIONSThe results suggest PSAD, FPSA/TPSA, especially PSAD-TZ could be used to distinguish BPH and PCa.