The distribution and detection of androgen receptor in extra-testis tissues.
- Author:
Lei-Lei CHEH
1
;
Bing YAO
;
Yu-Feng HUANG
Author Information
1. Laboratory of Reproduction & Genetics, Nanjing General Hospital of Nanjing Command, PLA, Nanjing, Jiangsu 210002, China.
- Publication Type:Journal Article
- MeSH:
Androgens;
metabolism;
Hippocampus;
metabolism;
Humans;
Male;
Penis;
metabolism;
Prostate;
metabolism;
Receptors, Androgen;
metabolism;
Testis;
metabolism;
Tissue Distribution;
Tumor Cells, Cultured
- From:
National Journal of Andrology
2003;9(1):51-54
- CountryChina
- Language:Chinese
-
Abstract:
Androgen receptor(AR) plays an important role in modulating the effects of androgen on target cells. It is well known that AR is mainly existed in testis. This paper reviewed the distribution of AR and its mRNA in prostate, epididymis, skin of penis, and some other tissues in non-genital system and tumors, such as the skin of scalp, hippocampus, fat, gastric cancer, cancer of larynx, and so on. Besides, this paper also reviewed the detection methods to AR, and further investigated the function of androgen.
