Advances in spermatogonial transplantation.
- Author:
Bo SONG
1
;
Zhi-Ming CAI
Author Information
1. Department of Andrology, Shenzhen Hospital of Peking University, Shenzhen, Guangdong 518036, China.
- Publication Type:Journal Article
- MeSH:
Animals;
Animals, Genetically Modified;
Humans;
Male;
Spermatogenesis;
physiology;
Spermatogonia;
transplantation;
Transplantation, Heterologous
- From:
National Journal of Andrology
2003;9(1):58-66
- CountryChina
- Language:Chinese
-
Abstract:
Spermatogonial transplantation (ST) is a novel technique which mechanism is similar to other transplantations. The donor testicular cells transferred into recipient testes by the microinjection can initiate spermatogenesis and produce sperm in the recipient testis. The homograft has got success. The xenograft in which (man, horse, bull or rat, can be the donor; immunodeficiency mouse can be the recipient) and cryopreserved germ cells can not clonize in the recipient testes. The reason may be immunoreaction. ST technique will be propitious to these fields, 1. to investigate fundamental aspects of spermatogenesis; 2. to regenerate spermatogenesis in infertile individuals; 3. to develop transgenic animals.
