Relationship between plasminogen activator, plasminogen activator inhibitor and Sertoli cells.
- Author:
Xiao-Yan WANG
1
;
Cheng-Liang XIONG
Author Information
1. Family Planning Research Institute, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China.
- Publication Type:Journal Article
- MeSH:
Humans;
Male;
Plasminogen Activators;
metabolism;
physiology;
Plasminogen Inactivators;
metabolism;
physiology;
Sertoli Cells;
metabolism;
physiology;
Testis;
cytology
- From:
National Journal of Andrology
2003;9(2):133-139
- CountryChina
- Language:Chinese
-
Abstract:
Plasminogen activator(PA) and plasminogen activator inhibitor(PAI) are involved in many physiological or pathological events. The Sertoli cells, the important elements within the seminiferous epithelium, are thought to play a key role in spermatogenesis. The Sertoli cells secrete PA and PAI. The levels of them are modulated by hormonal and cell-mediated influences. They play a fundamental role in the maintenance of spermatogenesis, sperm motility and fertilization.
