The effect of Chinese medicine yiqihuoxuetang on T-lymphocyte subpopulation in peripheral blood of infertile men with antisperm antibodies.
- Author:
Hua-Gang MA
1
;
Ji-Xiu XU
;
Jian-Fa ZHANG
;
Fang ZHANG
;
Qing-Tu WANG
;
Cheng-Liang XIONG
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Autoantibodies; immunology; CD4-CD8 Ratio; Drugs, Chinese Herbal; pharmacology; Humans; Infertility, Male; immunology; pathology; Male; T-Lymphocyte Subsets; drug effects
- From: National Journal of Andrology 2003;9(2):154-156
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVESTo study whether Chinese Medicine Yiqihuoxuetang(YQHXT) could inhibit antisperm antibodies in infertile men, and to explore the therapeutical mechanism of YQHXT.
METHODSThirty infertile men with antisperm antibodies took YQHXT continuously for 60 days. Indirect immuno-fluorescence technique (IFT) was used to detect the levels of CD3, CD4, CD8 and CD4/CD8 ratio before and after treatment.
RESULTSCD4 value and CD4/CD8 ratio after treatment were significantly lower than before treatment (P < 0.05); CD8 value became significantly higher(P < 0.05).
CONCLUSIONSThe results indicated that YQHXT could inhibit antisperm antibodies by keeping the balance of T-lymphocyte subpopulation in immunoinfertile men.
