Prevalence of sensitization to aeroallergens in 10030 patients with allergic rhinitis
10.3760/cma.j.issn.1673-0860.2011.11.008
- VernacularTitle:变应性鼻炎患者10030例吸人性变应原谱分析
- Author:
You YANG
1
;
Yan ZHAO
;
Cheng-Shuo WANG
;
Xiang-Dong WANG
;
Luo ZHANG
Author Information
1. 首都医科大学附属北京同仁医院
- Keywords:
Rhinitis,allergic,perennial;
Rhinitis,allergic,seasonal;
Allergens;
Skin tests
- From:
Chinese Journal of Otorhinolaryngology Head and Neck Surgery
2011;46(11):914-920
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the main inhaled allergens in patients with allergic rhinitis.Methods Forty-three standardization allergens were used to perform skin prick test in 54 813 patients with chronic rhinitis.According to different gender and age groups,10 030 patients with allergic rhinitis were divided into eight groups.The distributions of different allergens in the eight groups were analyzed.Results ①The most common four allergens in male patients with allergic rhinitis were Dermatophagoides farina (Der f),Dermatophagoides pteronyssinus (Der p ),Mugwort and Blaterlia Germanica.Der f,Der p,Mugwort and Chenopodium album were the most common in female patients.②In all groups,patients with dual positive allergens were the most common,followed by triple positive allergens and single positive allergen.③ In single positive allergen group,the top four allergen in male 3 - 17 year group were Derf,Der p,Alternaria tenuis and Mugwort.In other male groups,the most common positive allergen were Derf,Der p,Mugwort and Blaterlia Germanica.Meanwhile,the top four positive allergens in female 3 - 17 year group were Derf,Der p,Mugwort and Alternaria tenuis,in 18 -39 year group were Der f,Der P,Mugwort and Dandelion,in 40 -59 year group were Der f,Der p Mugwort and mixed tree 1,in ≥ 60 year group were Derf,Der P,mixed animal hair and Mugwort.④ In dual positive allergens group,the most common allergen combination was Derf + Der p,followed by Alternaria tenuis in patient of 3 - 17 year group.⑤ In triple positive allergens group,the most common allergen combination was Derf + Der p + Blaterlia Germanica,followed by Derf + Derp + mixed animal hair.Conclusions Dust mites,flowers pollen,herbs,Alternaria tenuis and Blaterlia Germanica were the most common allergens in patients with allergic rhinitis.However,the frequencies of the allergens were different in different age groups.