OBJECTIVETo analyze the mechanism of fluorine by systemic analysis of fluorination-demineralization-remineralization experiments.

METHODSThe enamel specimens were randomly assigned to untreated group (group A), non-fluoride group (group B), low-fluoride group (group C) and high-fluoride group (group D). The in vitro model of fluoride enamel was established in group C and D. Based on that, the establishment of demineralization model and remineralization experiment by pH-cycling in group B, C and D were followed. All enamel specimens were observed by stereomicroscope and scanning electron microscope and compared in surface microhardness value.

RESULTSThere was distinct difference in micro-morphologic appearance on fluoride enamel surface. Artificial caries of fluoride enamel showed a relatively complete surface, the surface microhardness after demineralization and remineralization in fluoride group was higher than non-fluoride group (P < 0.05).

CONCLUSIONThe fluorinated enamel can enhance cariostatic potential and remineralization capacity of dental enamel.