Study of the pragmatic of saliva test cassette to detect the Helicobacter pylori in oral cavity.
- Author:
Xiaomin WANG
1
;
Yan ZHAO
;
Nan CHEN
;
Junhong WANG
;
Yantong XING
;
Gengyue ZHANG
Author Information
- Publication Type:Journal Article
- MeSH: Bayes Theorem; Breath Tests; Helicobacter Infections; Helicobacter pylori; Humans; Mouth; Saliva; Sensitivity and Specificity; Urea
- From: West China Journal of Stomatology 2012;30(5):501-504
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the link of Helicobacter pylori salive test cassette (HPS) and 13C-urea breath test (13C-UBT) on detecting Helicobacter pylori infection of stomach, and the sensitivity as well as specificity should be determined.
METHODSA screening trial of 13C-UBT and HPS tests was carried out 130 patients included 106 positive and 24 negative results of 13C-UBT. As gold standards of 13C-UBT, a comparison study with HPS was evaluated using Bayes formula.
RESULTSThe sensitivity, specificity, accuracy, positive and negative predictive value of HPS was 68.87%, 58.33%, 66.92%, 87.95%, 29.79% respectively. The coincidence was 66.92%.
CONCLUSIONThere is a correlation between results of 13C-UBT and HPS. Combination of 13C-UBT and HPS may compensate the blind zone of 13C-UBT in detecting oral Helicobacter pylori infection. 13C-UBT could not be used as a gold standard to judge the validation of HPS in detecting Helicobacter pylori oral infection. The methods can be used at the same time in clinic.
