LDH activity in blood and cerebrospinal fluid in bacterial meningitis and viral meningitis
- Author:
Huy Vu Bui
- Publication Type:Journal Article
- Keywords:
Bacterial meningitis
- MeSH:
Meningitis;
cerebrospinal fluid;
blood;
Meningitis, Bacterial;
Meningitis, Viral
- From:Journal of Medical and Pharmaceutical Information
2001;(11):24-27
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
To evaluate the diagnostic value of lactate dehydrogenase (LDH) in bacterial meningitis (BM) and viral meningitis (VM), LDH was determined simultaneously in cerebrospinal fluid (CSF) and in sera of 89 children suffering from meningitis (51 BM and 38 VM) by 3 time (acute phase, 7-10 days later, and recovering period). Control group consists of 33 normal children. In blood, LDH activity was always elevated, statistically different from control group (p<0.05) but these was no difference between BM and VM. So LDH in sera isn't helpful in the differential diagnosis between BM and VM. In contrast, LDH activity in CSF was highly statistical difference from control group (p<0.001) and there was statistical different between BM and VM. Therefore, LDH activity in CSE has great value in the differential diagnosis between BM and VM; it possesses prognostic value in BM.
