Hand-Foot-Mouth Disease Related to Enterovirus 71.
10.5124/jkma.2009.52.9.886
- Author:
Jong Hyun KIM
1
;
Seong Joon KIM
;
Doo Sung CHEON
Author Information
1. Department of Childhood and Adolescent Medicine, College of Medicine, The Catholic University of Korea, Korea.
- Publication Type:Original Article
- Keywords:
Hand-foot-mouth disease;
Enterovirus 71;
Coxsackievirus A16;
Neurological complication;
Brain-stem encephalitis
- MeSH:
Disease Outbreaks;
Enterovirus;
Exanthema;
Republic of Korea
- From:Journal of the Korean Medical Association
2009;52(9):886-894
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Hand-foot-mouth disease (HFMD), one of the more distinctive rash syndromes, is most frequently caused by coxsackievirus A16, but can also be caused by enterovirus 71 (EV71) and other coxsackieviruses. Recently, there have been large outbreaks of simple, neurologically complicated and even fatal HFMD caused by EV71 in Western Pacific Area. However, in the Republic of Korea, despite its location in EV71 endemic Western Pacific Area, published reports on HFMD with EV71 are rare and there are no published reports on fatal cases. After the first fatal case of HFMD caused by EV71 announced in May 2009, much more cases of neurologically complicated HFMD have been announced. Even now, physician's increased awareness about the seriousness of HFMD, viral surveillance and early warning system of HFMD, and early detection and proper management of potentially life threatening HFMD caused by EV71 are required in the Republic of Korea, as in the neighboring countries.
