Correlation between magnetic resonance imaging findings and proliferating cell nuclear antigen expression in peripheral lung cancer.
- Author:
Zhi-ming XIANG
1
;
Yu-sheng HU
;
Shi-yu ZHAO
;
Li-lian TAN
;
Zhi-hua LI
Author Information
- Publication Type:Journal Article
- MeSH: Adenocarcinoma; pathology; Adult; Aged; Carcinoma, Squamous Cell; metabolism; pathology; Female; Humans; Immunohistochemistry; Lung Neoplasms; metabolism; pathology; Magnetic Resonance Imaging; Male; Middle Aged; Proliferating Cell Nuclear Antigen; metabolism
- From: Journal of Southern Medical University 2008;28(12):2230-2232
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the correlation between magnetic resonance imaging (MRI) findings and proliferating cell nuclear antigen (PCNA) expression in peripheral lung cancer.
METHODSThe expression of PCNA was detected by means of SABC immunohistochemistry in 45 cases of surgically and pathologically confirmed peripheral lung cancer. The correlation between PCNA expression in the tumors and the MRI findings was analyzed.
RESULTSPCNA expression was correlated to the differentiation, tumor size, lobulation, and mediastinal lymph node metastasis of the tumors (P<0.05), but not to the histological type, clinical stage, pleural retraction, spiculation, or signal feature.
CONCLUSIONCorrelations are found between MRI findings of lung cancer and abnormal expression of PCNA.
