Sero-epidemiological investigation on hepatitis B among permanent residents in Shenzhen area.
- Author:
Jin-quan CHENG
1
;
Han-wu MA
2
;
Xu XIE
2
;
Yan LU
2
;
Yan-biao ZHANG
2
;
Shu-xian DONG
3
;
Ting-zhe WANG
3
;
Yi-min LIU
4
;
Wen-hua LING
5
;
Yuan-tao HAO
5
Author Information
- Publication Type:Journal Article
- MeSH: Adolescent; Adult; Child; Child, Preschool; China; epidemiology; Female; Hepatitis B; blood; epidemiology; Humans; Infant; Male; Middle Aged; Seroepidemiologic Studies; Surveys and Questionnaires
- From: Chinese Journal of Epidemiology 2013;34(12):1179-1182
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo understand the infection status and epidemiological features of HBV in permanent residents of Shenzhen city.
METHODSA multi-stage stratified random sampling method was performed for questionnaire survey to permanently-registered residents of 1-59 years old in Luohu and Baoan district of Shenzhen in 2010, and blood samples of the subjects were collected. Hepatitis B virus-related surface antigen (HBsAg) and hepatitis B virus surface antibody (anti-HBs) were detected with ELISA.
RESULTSThe total 3771 studied population showed 252 HBsAg positive and 2712 anti-HBs positive residents with the standardization prevalence as 9.73% and 72.83% , respectively. The difference of the prevalence of HBsAg and anti-HBs between males and females were not statistically significant (P > 0.05). The prevalence of HBsAg was reduced with increasing age. The differences of the prevalence of HBsAg between Shenzhen permanent registered and non-permanent registered population were not significant, but the prevalence of anti-HBs in Permanent registered residents (78.32%) was higher than in non-permanent (66.03%, χ(2) = 41.613, P < 0.001). The prevalence of HBsAg was significantly different in various occupational and educational levels. Peasants had the highest prevalence (24.13%) and medical workers had the highest prevalence of anti-HBs (89.10% ). People with junior high school education had the highest prevalence of HBsAg (12.76%) and the lowest of anti-HBs (62.45%). Population with high-level education had the highest prevalence of anti-HBs(81.00% average). The prevalence of HBsAg was over 10% in people who were born in Shenzhen and Guangdong province, and the anti-HBs was the highest in Shenzhen population with the prevalence as 74.48% and 76.47% , respectively.
CONCLUSIONIn the Shenzhen resident population, the overall prevalence of HBV was lower than the average level of Guangdong province, but higher than the national wide.